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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1B
All Species:
6.97
Human Site:
T1521
Identified Species:
11.79
UniProt:
Q9UPS6
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPS6
NP_055863.1
1923
208732
T1521
Q
T
P
V
F
P
S
T
H
D
P
R
T
V
T
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
P1331
P
A
A
L
F
S
S
P
A
D
E
V
L
E
A
Rhesus Macaque
Macaca mulatta
XP_001092031
624
66545
R263
D
T
A
Y
S
S
C
R
L
D
T
P
N
S
Y
Dog
Lupus familis
XP_543382
1925
209302
T1524
Q
T
P
V
F
P
S
T
H
D
P
R
A
V
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
A1584
P
A
P
I
F
P
S
A
H
D
P
R
A
V
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510235
695
75024
Y334
N
R
R
H
E
H
H
Y
V
H
N
S
S
G
A
Chicken
Gallus gallus
Q5F3P8
2008
223067
S1615
V
P
V
A
L
V
E
S
A
M
S
K
E
L
L
Frog
Xenopus laevis
Q66J90
1938
216239
Q1553
G
K
Q
L
F
I
G
Q
P
D
S
V
S
G
I
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
D1451
K
N
K
K
G
I
Q
D
S
E
E
P
Q
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
G1279
V
S
Q
M
T
R
T
G
P
G
R
P
R
K
D
Honey Bee
Apis mellifera
XP_395451
1406
159180
D1045
V
K
L
S
K
N
K
D
K
T
H
K
V
E
K
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
P1146
D
N
V
A
E
T
G
P
L
I
Y
M
D
V
V
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
S1534
K
D
K
L
D
Q
S
S
S
D
T
D
K
G
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
P952
A
K
S
Q
V
G
E
P
E
P
V
P
E
P
E
Conservation
Percent
Protein Identity:
100
37.3
27.9
91.9
N.A.
87.7
N.A.
N.A.
23.1
61.5
55
51
N.A.
24.7
23.9
22.3
21.3
Protein Similarity:
100
50.3
28.8
93.9
N.A.
90.2
N.A.
N.A.
26.7
71.1
66.6
63.6
N.A.
39.4
38.6
35.2
35.2
P-Site Identity:
100
20
13.3
93.3
N.A.
66.6
N.A.
N.A.
0
0
13.3
13.3
N.A.
0
0
6.6
13.3
P-Site Similarity:
100
26.6
13.3
93.3
N.A.
73.3
N.A.
N.A.
6.6
20
26.6
26.6
N.A.
20
6.6
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
15
15
0
0
0
8
15
0
0
0
15
0
15
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
15
8
0
0
8
0
0
15
0
50
0
8
8
0
8
% D
% Glu:
0
0
0
0
15
0
15
0
8
8
15
0
15
15
8
% E
% Phe:
0
0
0
0
36
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
8
8
15
8
0
8
0
0
0
22
0
% G
% His:
0
0
0
8
0
8
8
0
22
8
8
0
0
0
0
% H
% Ile:
0
0
0
8
0
15
0
0
0
8
0
0
0
0
8
% I
% Lys:
15
22
15
8
8
0
8
0
8
0
0
15
8
8
8
% K
% Leu:
0
0
8
22
8
0
0
0
15
0
0
0
8
8
8
% L
% Met:
0
0
0
8
0
0
0
0
0
8
0
8
0
0
0
% M
% Asn:
8
15
0
0
0
8
0
0
0
0
8
0
8
0
0
% N
% Pro:
15
8
22
0
0
22
0
22
15
8
22
29
0
8
0
% P
% Gln:
15
0
15
8
0
8
8
8
0
0
0
0
8
0
0
% Q
% Arg:
0
8
8
0
0
8
0
8
0
0
8
22
8
0
0
% R
% Ser:
0
8
8
8
8
15
36
15
15
0
15
8
15
8
0
% S
% Thr:
0
22
0
0
8
8
8
15
0
8
15
0
8
0
29
% T
% Val:
22
0
15
15
8
8
0
0
8
0
8
15
8
36
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
8
0
0
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _